Diabetes mellitus results from immune-cell invasion into pancreatic islets of Langerhans, eventually
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Normal Insulin Secretion from Immune-Protected Islets of Langerhans by PEGylation and Encapsulation in the Alginate-Chitosan-PEG
Background: Pancreatic islet transplantation is one of the most promising strategies for treating patients with type I diabetes mellitus.Objective: We aimed to assess the immunoisolation properties of the multilayer encapsulated islets using alginate-chitosan-PEG for immunoprotection and insulin secretion from the encapsulated islets induced under differe...
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